Towards dynamic control of magnetic fields to focus magnetic carriers to targets deep inside the body.

نویسنده

  • Benjamin Shapiro
چکیده

Magnetic drug delivery has the potential to target therapy to specific regions in the body, improving efficacy and reducing side effects for treatment of cancer, stroke, infection, and other diseases. Using stationary external magnets, which attract the magnetic drug carriers, this treatment is limited to shallow targets (<5 cm below skin depth using the strongest possible, still safe, practical magnetic fields). We consider dynamic magnetic actuation and present initial results that show it is possible to vary magnets one against the other to focus carriers between them on average. The many remaining tasks for deep targeting in-vivo are then briefly noted.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of static magnetic field on the hemodynamic properties of blood flow containing magnetic substances

The use of magnetic fields in targeted drug delivery, especially for treatment of cancers and tumoral regions, is one of the significant techniques in the field of modern methods of treatment. Considering that many vital biological tissues have been located deep in the body, then for targeted drug delivery and effective treatment in these tissues, it is required to bring therapeutic agent to th...

متن کامل

Magnetic Nanoporous Silica as Carriers for Ibuprofen: Adsorption and Release Study

A carrier system based on nanoporous silica (SBA-15) with magnetic nanoparticles of CoFe2O4 was synthesized via the impregnation of cobalt salt, iron salt and citric acid with as-synthesized SBA-15. The obtained samples were characterized by small angle X-ray scattering (SAXS), N2 adsorption/desorption, scanning electron microscopy (SEM), vibrating sample magnetometer (VSM) and ultraviolet (UV)...

متن کامل

Magnetic Nanoporous Silica as Carriers for Ibuprofen: Adsorption and Release Study

A carrier system based on nanoporous silica (SBA-15) with magnetic nanoparticles of CoFe2O4 was synthesized via the impregnation of cobalt salt, iron salt and citric acid with as-synthesized SBA-15. The obtained samples were characterized by small angle X-ray scattering (SAXS), N2 adsorption/desorption, scanning electron microscopy (SEM), vibrating sample magnetometer (VSM) and ultraviolet (UV)...

متن کامل

A finite element model to simulate magnetic field distribution and laboratory studies in wet low-intensity magnetic separator

Low-intensity magnetic separators are widely used in the research works and the industry. Advancement in the magnetic separation techniques has led to an expansion in the application of this method in different fields such as enrichment of magnetic mineral, wastewater treatment, and medicine transfer in the human body. In the mineral processing industry, the main application of wet magnetic sep...

متن کامل

Open challenges in magnetic drug targeting - onlineLibraryTPS.asp

The principle of magnetic drug targeting, wherein therapy is attached to magnetically responsive carriers and magnetic fields are used to direct that therapy to disease locations, has been around for nearly two decades. Yet our ability to safely and effectively direct therapy to where it needs to go, for instance to deep tissue targets, remains limited. To date, magnetic targeting methods have ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Journal of magnetism and magnetic materials

دوره 321 10  شماره 

صفحات  -

تاریخ انتشار 2009